CaC Program Meeting
Discussion Leader:  Linda Cook and Angela Meisner, UNM
Discussion Topic:  Endometrial Cancer Epidemiology: Successes and Challenges

CaC Work-in-Progress Brown Bag Meeting
Discussion Leader:  Jean McDougall, UNM
Discussion Topic:  To be announced

Joint Program Meeting
Cancer Therapeutics
Cancer Genetics, Epigenetics & Genomics
Translational Cancer Biology & Signaling

New Opportunities: Target Validation

Discussion Leaders: Cedric Cleyrat & Alexandre Chigaev
This discussion about target validation led by Cedric Cleyrat will consider methods such as CRISPR Cas available to regulate expression of proteins in cells and their therapeutic value. We will assess the interest of UNMCCC investigators in such approaches to prioritize their use and adoption.

Lunch to be provided

This course offers the basic navigation of Mosaiq Application to include the following:

• Setting up the Home screen
• Adding additional tabs
• Viewing all patient notes
• Customizing patient chart tabs
• Navigating schedules to include daily, weekly views.
• Changing the dates
• Customizing the toolbar with shortcut items.
• Clinician worksheet navigation (Provider related)

Clinical Leader, Fa Chyi Lee, MD
Basic Science Leader, Ashwani Rajput, MD

As always:  These dates, times, and locations are subject to change – sometimes at short notice. Don’t hesitate to contact Karen directly if you have any questions.

• Ursa Brown-Glaberman, chair
• Reviews of PDSG, Clinical Pathways and Patient/Family Services meetings
• Scientific presentation regarding new technologies in breast cancer detection and treatment

Please contact Becky Lindley, admin support, if you have any questions regarding these meetings.

New Opportunities and Target Prioritization Meeting

Discussion Leaders: Bryce Chackerian PhD, UNM

Discussion Topic: VLP Update

Lunch provided.

Translation of Genomic and Microenvironmental Signals into Therapeutic Strategies Using Functional Approaches

Presented by:
Jeffrey W. Tyner, PhD
Associate Professor, Department of Cell, Developmental & Cancer Biology, Knight Cancer Institute, Oregon Health & Science University, Portland

Broad application of gene-targeted therapies in cancer has been challenging due to genetic heterogeneity as well as the lack of therapeutics to directly target many oncogenic drivers. While many new and exciting agents are emerging for inhibition of previously undruggable targets, there remain many cancer targets that can never be directly drugged due to their loss-of-function impact. To overcome these obstacles, my research program has developed a functional genomics pipeline for analysis of primary cells from patients with hematologic malignancies. In this lecture, I will provide an overview of these functional screening platforms, I will illustrate strategies of data integration that have enabled rapid discovery and translation of new targeted therapy strategies, and I will discuss our experience to date with direct clinical implementation of findings from these functional screening data.

Join us for the Lobos Love Pink UNM Men’s Basketball Game on Valentine’s Day. The UNM Comprehensive Cancer Center is promoting breast cancer awareness throughout the game.

Get there early for Lobos Love Pink giveaways!